Psychiatric Technician Practice Exam 2026 - Free Practice Questions and Study Guide

Long-term therapy with phenobarbital is associated with deficiencies in vitamins B9 (folate), B12, and D. Phenobarbital, a barbiturate that is commonly used as an anticonvulsant, can interfere with the metabolism and absorption of certain vitamins.

Vitamin B9 is essential for DNA synthesis and repair, and its deficiency can lead to anemia and other health issues. Similarly, Vitamin B12 is vital for red blood cell formation and neurological function, and its deficiency can result in significant neurological problems and anemia.

Vitamin D is important for calcium absorption and bone health. Phenobarbital can impact vitamin D metabolism, potentially leading to bone density issues such as osteomalacia or osteoporosis if deficiency occurs.

Understanding the associations of these deficiencies with long-term phenobarbital use highlights the importance of monitoring vitamin levels in patients undergoing this type of treatment, as well as the need for possible supplementation or dietary adjustments to prevent adverse health effects.